Succinylcholine vs. Rocuronium: Key Differences, Contraindications, and Myalgia Prevention According to the Society of Critical Care Medicine (SCCM), succinylcholine is contraindicated in patients at risk for hyperkalemia, malignant hyperthermia, or certain neuromuscular disorders. In contrast, rocuronium’s primary contraindication is hypersensitivity. Succinylcholine is associated with postoperative myalgia, especially in ambulatory patients. Evidence shows that pretreatment with nondepolarizin
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