Salt-inducible kinase 2 (SIK2) is a serine/threonine kinase that regulates transcriptional programs in myeloid cells by phosphorylating transcriptional coregulators. In macrophages, SIK2 promotes the ...
Researchers have developed and validated an artificial intelligence (AI) tool that can accurately distinguish ulcerative colitis (UC) remission from activity (inflammation) in biopsies and help ...
For patients who experience endoscopic remission of ulcerative colitis (UC), signs of active disease on histology did not affect their risk of clinical relapse, according to a large prospective study ...
Intestinal ultrasound (IUS) is non-invasive, cost-effective, and accurate to determine disease activity in ulcerative colitis (UC). In this study, we prospectively evaluated IUS for treatment response ...
In this Journal feature, information about a real patient is presented in stages (boldface type) to an expert clinician, who responds to the information by sharing relevant background and reasoning ...
EQ504 is an oral, selective aryl hydrocarbon receptor (AhR) modulator with colon-specific delivery that Equillium says is differentiated by targeting immune modulation, barrier function, and mucosal ...
Why Do People Get a Colonoscopy for Ulcerative Colitis? Ulcerative colitis is a type of inflammatory bowel disease that causes inflammation and sores to form in the large intestine and rectum. It ...
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