What do cells do when they are “hungry”? Eukaryotic cells cope with starving conditions by eating their own components, a process called autophagy. Aa Aa Aa Normally, when you are hungry you look for ...

Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged organelles, and unwanted molecules using powerful digestive enzymes. Lysosomes ...

Lysosomes are membrane-bound organelles whose acidic lumen (pH 4.5–5.0) is required for degradation. This luminal acidity is known to regulate cytosolic-side functions such as membrane fusion/fission, ...

Janelia researchers have uncovered a novel way that two of the structures inside cells—the endoplasmic reticulum (ER) and lysosomes—coordinate the production of proteins, highlighting how interactions ...

Ishikawa, Japan - The correct functioning of our cells rests upon the precise orchestration of many complex processes and organelles. Lysosomes—vital cell organelles—are enzyme-filled subunits found ...

Osteoporosis is a common skeletal disorder characterized by excessive bone loss, leading to increased fragility and an increased risk of fractures. Osteoclasts, the bone-resorbing cells, are widely ...

Researchers at the Icahn School of Medicine at Mount Sinai have discovered how to reverse aging in blood-forming stem cells in mice by correcting defects in the stem cell's lysosomes. The breakthrough ...

Northwestern Medicine scientists have identified the consequences of contact between the mitochondria and the lysosome in the axons and synapses of human neurons, according to a study published in ...

Mutations in the progranulin gene cause a form of frontotemporal dementia, most likely because levels of the protein fall in the central nervous system. How this affects brain function is unknown.

Transmission electron microscopic image of an isolate from the first U.S. case of COVID-19, formerly known as 2019-nCoV. The spherical viral particles, colorized blue, contain cross-section through ...